Module 5.5: Pentose Phosphate Pathway

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Welcome! Pentose Phosphate Pathway (5.5) — 16 questions across 1 tests.

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Test 1 (5.5) — Pentose Phosphate Pathway

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5.5 Pentose Phosphate Pathway — Test 1

Q1. In highly proliferating cells there is an enhanced rate of anabolic reactions as well as nucleic-acid synthesis. Which pathway facilitates these requirements?✓ HMP shunt (pentose phosphate pathway)

Q2. An alternative to the glycolysis pathway is:✓ Pentose phosphate pathway

Q3. Which of the following is involved in the pentose phosphate pathway?✓ Glucose-6-phosphate dehydrogenase

Q4. The antimalarial drug primaquine causes RBC lysis and jaundice in some people. This is due to a deficiency in the enzyme:✓ Glucose-6-phosphate dehydrogenase

Q5. During the introduction of pamaquine (1926), an antimalarial, several patients died of massive RBC destruction (haemolytic anaemia). The condition was later identified as a deficiency of which PPP enzyme?✓ Glucose-6-phosphate dehydrogenase

Q6. The connecting link between the HMP shunt and lipid synthesis is:✓ NADPH

Q7. In highly proliferating cells there are enhanced anabolic reactions and nucleic-acid synthesis. Which pathway facilitates this?✓ HMP shunt

Q8. Which one of the following metabolites is NOT directly produced in the hexose monophosphate shunt pathway?✓ Dihydroxyacetone phosphate

Q9. Which one of the following metabolites is NOT directly produced in the hexose monophosphate pathway? (variant)✓ Dihydroxyacetone phosphate

Q10. Which of the following metabolites is NOT directly produced in the hexose monophosphate pathway? (variant)✓ Dihydroxyacetone phosphate

Q11. Which of the following pentoses is NOT formed during the pentose phosphate pathway?✓ Xylose-5-phosphate

Q12. Interconversion of hexoses and pentoses is catalyzed by:✓ Transaldolase and transketolase

Q13. The 3-carbon (3C) intermediate of the pentose phosphate pathway is:✓ Glyceraldehyde-3-phosphate

Q14. Which enzyme forms a Schiff base with sedoheptulose-7-phosphate (S7P)?✓ Transaldolase

Q15. Transketolase in the pentose phosphate pathway requires which B vitamin?✓ Thiamine

Q16. The transketolase enzyme in the pentose phosphate pathway requires which one of the following B vitamins? (variant)✓ Thiamine