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6.1 Fatty Acid Oxidation β Test 1
Q1. Fatty acids enter the Krebs cycle as:β A two-carbon fragment (acetyl-CoA)
Q2. Ξ±-oxidation of fatty acids mainly occurs in:β Brain
Q3. Ξ±-oxidation of fatty acids occurs in:β Peroxisomes
Q4. Ξ²-oxidation primarily refers to the:β Breakdown of fatty acids
Q5. Ξ²-oxidation takes place in:β Mitochondria
Q6. Each cycle of Ξ²-oxidation produces:β 1 FADHβ, 1 NADH and 1 acetyl-CoA
Q7. Each cycle of Ξ²-oxidation produces how many molecules of each? (variant)β 1 FADHβ, 1 NADH and 1 acetyl-CoA
Q8. The enzymatic steps in the first stage of saturated fatty acid oxidation occur in the order:β Acyl-CoA dehydrogenase β enoyl-CoA hydratase β hydroxyacyl-CoA dehydrogenase β thiolase
Q9. Which of the following can undergo Ξ²-oxidation?β All of these
Q10. How do fatty acid Ξ²-oxidation and biosynthesis differ in cellular location?β Oxidation in mitochondria; biosynthesis in cytoplasm
Q11. Carnitine palmitoyl transferase I (CPT-I) is responsible for carrying:β Long-chain fatty acids into mitochondria
Q12. Carnitine palmitoyl transferase I (CPT-I) is responsible for carrying: (variant)β Long-chain fatty acids into mitochondria
Q13. Ξ²-oxidation involves the activation of fatty acids in the presence of:β ATP and thiokinase enzyme
Q14. Which of the following is an anti-lipolytic hormone?β Insulin
6.1 Fatty Acid Oxidation β Test 2
Q15. The hydrolysis of fat is accelerated by the presence of which ion?β CaΒ²βΊ
Q16. Which pair of lipids/related compounds exhibits opposite biological activities?β Thromboxane A2 and prostacyclin
Q17. Formation of fat begins in the body when:β Liver and muscles cannot store any more glycogen
Q18. Lipolysis is inhibited by:β Insulin
Q19. The direct products of oxidation of a fully saturated, straight-chain fatty acid of 13 carbons are:β 5 acetyl-CoA and 1 propionyl-CoA
Q20. The direct products of Ξ²-oxidation of a fully saturated, straight-chain fatty acid of 17 carbons are:β 7 acetyl-CoA and 1 propionyl-CoA
Q21. To fully oxidize a saturated 13-carbon fatty acid, besides the Ξ²-oxidation enzymes, one additional enzyme required is:β Methylmalonyl-CoA mutase
Q22. Neutral lipids stored in adipocytes as droplets are surrounded by a protein called:β Perilipin
Q23. Enzymes from which organelle oxidize fatty acids, but the released energy is NOT used for ATP synthesis?β Peroxisomes
Q24. Riboflavin is a coenzyme in the reaction catalyzed by:β Acyl-CoA dehydrogenase
Q25. How do statins lower blood cholesterol concentrations?β Inhibit HMG-CoA reductase
Q26. How do statins lower blood cholesterol? (variant)β Inhibit HMG-CoA reductase
Q27. In Ξ²-oxidation, 3-ketoacyl-CoA is split at the 2,3-position by:β Ξ²-ketothiolase (acyl-CoA acetyltransferase)