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6.2 Fatty Acid Biosynthesis โ Test 1
Q1. Which one of the following enzymes is activated by phosphorylation?โ Fructose-2,6-bisphosphatase
Q2. Which is the prosthetic group of acyl carrier protein, and the enzyme that condenses acyl and malonyl groups?โ 4'-phosphopantetheine & ฮฒ-ketoacyl-ACP synthase
Q3. The acetyl groups required for cytoplasmic fatty acid biosynthesis are generated due to the activity of:โ Citrate lyase
Q4. Which enzyme is NOT part of the fatty acid synthase complex?โ ฮฑ-hydroxyacyl-CoA dehydrogenase
Q5. If ยนโดC-malonyl-CoA (labelled at carbon 2) and acetyl-CoA are used with fatty acid synthase, which carbons of palmitic acid will be labelled?โ All even-numbered carbons except carbon 16
Q6. If ยนโดC-malonyl-CoA (labelled at carbon 2) and acetyl-CoA are used in vitro with fatty acid synthase, which carbon of palmitic acid will be labelled? (variant)โ All even-numbered carbons except carbon 16
Q7. Where does endogenous fatty acid synthesis predominantly occur in humans?โ Lactating mammary gland
Q8. The synthesis of the monounsaturated fatty acid palmitoleate 16:1(ฮ9) from palmitate is catalysed by fatty acyl-CoA desaturase, which is a:โ Mixed-function oxidase
Q9. The precursor for fatty acid biosynthesis is:โ Acetyl-CoA
Q10. The reducing power required for fatty acid biosynthesis in the liver is provided by:โ Hexose monophosphate (HMP) shunt
Q11. Which statement about NADPH for fatty acid synthesis is true?โ It comes from the HMP shunt pathway
Q12. NADPH for fatty acid synthesis is generated from:โ HMP shunt pathway
Q13. NADPH required for fatty acid synthesis can be generated from: (variant)โ HMP shunt pathway