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7.3–7.4 Biosynthesis & One-Carbon — Test 1
Q1. What enzyme does the LEU2 gene code for?✓ β-isopropylmalate dehydrogenase
Q2. The biosynthetic pathway of which amino acid is similar to purine biosynthesis?✓ Histidine
Q3. Which of the following provides atoms to form histidine?✓ Phosphoribosylpyrophosphate (PRPP)
Q4. In plants, the first step in the synthesis of sulfur-containing organic compounds is the reduction of sulfate. Which amino acid is synthesized in this process?✓ Cysteine
Q5. Which one of the following is NOT an anabolic product of nitrogen assimilation?✓ Urea
Q6. Deficiency of which cofactor adversely affects the synthesis of purines and pyrimidines?✓ Folate
Q7. The micronutrient essential for synthesis of purines is:✓ Folic acid
Q8. Which statement about one-carbon transfer in purine/pyrimidine synthesis is correct?✓ N10-formyl-THF is used as a one-carbon donor in purine synthesis
Q9. Which statements about one-carbon transfer reactions in purine and pyrimidine nucleotide synthesis are correct?✓ N10-formyl-THF is the one-carbon donor in purine synthesis; N5,N10-methylene-THF is used in dTMP synthesis