Membrane Transport (9.2)

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  • Test 1 (9.2) — Membrane Transport

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9.2 Membrane Transport β€” Test 1
Q1. Which of the following are endocytic receptors?βœ“ LDL receptor and cation-independent mannose-6-phosphate receptor
Q2. All statements about transfer of damaged plasma-membrane proteins to the lysosome are true EXCEPT:βœ“ The process is independent of ESCRT proteins
Q3. The proteins that form channels between two neighbouring cells, connecting their cytoplasms, are:βœ“ Connexins (gap junctions)
Q4. The superfamily of membrane transporters that actively transports a variety of small molecules (sugars, peptides, amino acids) using ATP is:βœ“ ABC transporter
Q5. Fatty acids are transported across the cell membrane mainly by:βœ“ Facilitated transport
Q6. The glucose transporter expressed predominantly in liver (and pancreatic Ξ²-cells) is:βœ“ GLUT2
Q7. The glucose transporter expressed mainly in liver cells is (variant):βœ“ GLUT2
Q8. GLUT3, a class I facilitative glucose transporter, is mainly present in:βœ“ Brain (neurons)
Q9. Lactose uptake in E. coli is mediated by:βœ“ Secondary active transport
Q10. The Na⁺/K⁺-ATPase maintains the membrane potential by pumping:βœ“ Na⁺ and K⁺ in opposite directions, each against its gradient
Q11. Which amino-acid residue is transiently phosphorylated during the Na⁺/K⁺-ATPase cycle?βœ“ Aspartic acid
Q12. Which residue is phosphorylated during sodium–potassium ATPase function? (variant)βœ“ Aspartic acid
Q13. Valinomycin is an ionophore responsible for the downhill transmembrane transport of:βœ“ K⁺
Q14. Gramicidin A differs from valinomycin in that it:βœ“ Forms a transmembrane channel permeable to monovalent cations
Q15. In secondary active transport, the energy to move a solute against its gradient comes from:βœ“ An electrochemical ion gradient (e.g. Na⁺ or H⁺) set up by a primary pump
Q16. The mitochondrial ADP/ATP translocase (adenine nucleotide translocator) exchanges:βœ“ ADP in for ATP out across the inner membrane
Q17. Aquaporins increase membrane permeability specifically to:βœ“ Water
Q18. During receptor-mediated endocytosis (e.g. of LDL), the coat protein that forms the invaginating vesicle is:βœ“ Clathrin
Q19. In facilitated diffusion, the transported solute moves:βœ“ Down its concentration gradient via a specific carrier/channel, without ATP
Q20. Macromolecules pass between the nucleus and cytoplasm through:βœ“ Nuclear pore complexes
Q21. An ionophore that collapses a membrane H⁺ gradient by carrying protons across the bilayer acts as a(n):βœ“ Uncoupler / protonophore