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1.1 Scope, Branches & Applications — Test 1
Q1. Bioinformatics is best defined as the branch that deals with the:✓ Application of computational tools to store, analyse and interpret biological data
Q2. The branch of bioinformatics that concentrates on aspects dealing with drug discovery is:✓ Pharmacoinformatics
Q3. Comparative genomics is mainly concerned with:✓ Comparing the genomes of different organisms
Q4. Functional genomics primarily aims to understand the:✓ Functions and interactions of genes and their products
Q5. The US-based organisation that maintains GenBank, BLAST and PubMed is the:✓ NCBI (National Center for Biotechnology Information)
Q6. Open-source bioinformatics tools are often distributed under the GPL, which stands for:✓ General Public License
Q7. The role of the internet and the World Wide Web in bioinformatics is mainly to:✓ Provide access to shared databases and online analysis tools
Q8. Proteomics is the large-scale study of:✓ The complete set of proteins (the proteome)
Q9. Margaret Dayhoff, an early pioneer of bioinformatics, is especially known for developing:✓ The first protein sequence atlas and PAM scoring matrices
Q10. The term 'in silico' refers to biological analysis carried out:✓ By computer
Q11. A sequence-alignment tool provided by NCBI to find regions of local similarity is:✓ BLAST
Q12. Cheminformatics differs from bioinformatics in that it focuses on:✓ Chemical (e.g. small-molecule) data and their analysis
Q13. Structural bioinformatics is mainly concerned with the analysis and prediction of:✓ Three-dimensional structures of biomolecules
Q14. Applications of bioinformatics include all of the following EXCEPT:✓ Physically synthesising a protein in a test tube
Q15. The European counterpart of NCBI, hosting databases such as EMBL-Bank, is the:✓ EBI (European Bioinformatics Institute)
Q16. Genomics, as a discipline, is the study of:✓ The structure, function and evolution of genomes
Q17. Systems biology, supported by bioinformatics, aims to understand biology by studying:✓ Networks and interactions among many components together
Q18. Pharmacogenetics, related to but distinct from pharmacoinformatics, studies how:✓ An individual's genes affect their response to drugs
Q19. A major reason biological databases are central to bioinformatics is that they:✓ Store and organise vast amounts of biological data for retrieval and analysis
Q20. Match each branch/term with its focus and select the correct option.✓ A-iii, B-iv, C-i, D-ii