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3.6 Phylogenetic Tree Construction — Test 1
Q1. A phylogenetic tree is a diagram that represents the:✓ Evolutionary relationships among sequences or organisms
Q2. In a phylogenetic tree, the tips (leaves) usually represent:✓ The taxa or sequences being compared
Q3. An internal node in a phylogenetic tree represents a:✓ Hypothetical common ancestor
Q4. Branch lengths in many phylogenetic trees indicate the:✓ Amount of evolutionary change (e.g. substitutions)
Q5. A rooted tree differs from an unrooted tree in that a rooted tree:✓ Indicates the direction of evolution from a common ancestor
Q6. Distance-based methods of tree building include:✓ UPGMA and neighbour-joining
Q7. Character-based tree-building methods include:✓ Maximum parsimony and maximum likelihood
Q8. The maximum parsimony method selects the tree that:✓ Requires the fewest evolutionary changes
Q9. Maximum likelihood tree building differs from parsimony in that it:✓ Uses an explicit statistical model of sequence evolution
Q10. UPGMA makes the simplifying assumption of a:✓ Constant rate of evolution (molecular clock)
Q11. Bootstrapping is used in phylogenetics to:✓ Estimate the statistical support/confidence for branches
Q12. An outgroup is included in a phylogenetic analysis mainly to:✓ Root the tree and orient the direction of evolution
Q13. A clade (monophyletic group) consists of:✓ An ancestor and all of its descendants
Q14. The usual input for building a phylogenetic tree from sequences is a:✓ Multiple sequence alignment
Q15. Neighbour-joining is popular because it:✓ Is fast and does not assume a constant evolutionary rate
Q16. The branching pattern (shape) of a tree, irrespective of branch lengths, is called its:✓ Topology
Q17. A high bootstrap value (e.g. 95%) for a branch indicates that the branch is:✓ Strongly supported by the data
Q18. The taxa or sequences placed at the tips of a tree are sometimes called:✓ Operational taxonomic units (OTUs)
Q19. Distance-based methods such as neighbour-joining build the tree from a:✓ Matrix of pairwise distances between sequences
Q20. Match each phylogenetics term/method with its description and select the correct option.✓ A-ii, B-i, C-iv, D-iii