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2.2 Sperm Maturation — Test 1
Q1. Capacitation of mammalian sperm is best described as:✓ Maturation of sperm within the female reproductive tract that enables fertilization
Q2. Sperm that are morphologically normal but cannot become hyperactivated and swim vigorously are lacking:✓ Capacitation
Q3. In humans, capacitation of sperm takes place mainly in the:✓ Ampulla of the oviduct
Q4. A key membrane change during capacitation is the removal of:✓ Cholesterol from the sperm head membrane
Q5. The acrosome reaction involves:✓ Exocytosis of acrosomal enzymes that help the sperm penetrate the egg coats
Q6. Hyperactivation of sperm refers to:✓ A vigorous, whip-like flagellar beat that aids penetration of the egg coats
Q7. Membrane-bound, Golgi-derived structures containing proteolytic enzymes in the sperm head are the:✓ Acrosomal vesicles
Q8. The experiment in which mouse epididymal sperm failed to fertilize in a dish but succeeded inside the female tract shows that:✓ The female reproductive tract activates the sperm (capacitation)
Q9. During capacitation, sperm also lose non-covalently bound:✓ Glycoproteins from the surface
Q10. Capacitation generally results in changes that:✓ Increase membrane fluidity and intracellular pH and Ca2+
Q11. The acrosome reaction normally occurs:✓ After capacitation, as the sperm reaches the egg coats
Q12. Epididymal maturation of sperm (before capacitation) mainly provides:✓ Motility potential and surface modifications
Q13. Bicarbonate and calcium ions promote capacitation largely by:✓ Activating signalling (e.g. cAMP) that changes sperm behaviour
Q14. The main purpose of the acrosome reaction is to allow the sperm to:✓ Penetrate the egg's outer coats and reach its membrane