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3.3 Population Genetics: Hardy-Weinberg — Test 2
Q1. All the alleles of all the genes present in a Mendelian population together make up its:✓ Gene pool
Q2. The Hardy-Weinberg law applies to a:✓ Large, random-mating population
Q3. In a population at Hardy-Weinberg equilibrium, one allele has frequency 0.2 and the other 0.8. In a population of 250, the number of homozygous individuals is:✓ 170
Q4. The Hardy-Weinberg law is most useful for:✓ Estimating allele frequencies
Q5. A recessive disease occurs in 16% of a population at Hardy-Weinberg equilibrium. The frequency of the dominant allele is:✓ 0.6
Q6. If a gene has three alleles p, q and r, the Hardy-Weinberg genotype frequencies are given by:✓ (p + q + r)²
Q7. In a Hardy-Weinberg population, the frequency of heterozygotes is highest when:✓ p = q = 0.5
Q8. In a Hardy-Weinberg population, the recessive allele has frequency 0.88 and the dominant 0.12. The frequency of heterozygotes is approximately:✓ 21.1%
Q9. A disease allele is recessive; its homozygous-recessive frequency in a population of 10,000 corresponds to an allele frequency of 0.04. The number of affected individuals is:✓ 16
Q10. In the Hardy-Weinberg equation, the symbols p and q represent:✓ Allele frequencies
Q11. In a population, two alleles B (0.7) and b (0.3) are at Hardy-Weinberg equilibrium. In a sample of 250, the number of heterozygotes (Bb) is:✓ 105
Q12. Which of the following is NOT an assumption of the Hardy-Weinberg rule?✓ Small population size
Q13. The Hardy-Weinberg law will NOT hold (for an autosomal locus) when:✓ There is a strongly skewed sex ratio with non-random mating
Q14. Red hair is recessive. If 9% of individuals in a Hardy-Weinberg population are red-haired, the frequency of heterozygous carriers is:✓ 42%
Q15. In a sample of 400 individuals, 36 are homozygous for the recessive allele a. The number carrying at least one dominant allele A is:✓ 364
Q16. If the frequency of recessive homozygotes q² = 0.04 in a Hardy-Weinberg population, the percentage of individuals homozygous for the dominant allele is:✓ 64
Q17. A blood group O occurs in 25% of a population, and the alleles for A and B are equally frequent. The ratio of allele frequencies O : A : B is:✓ 2 : 1 : 1
Q18. A recessive autosomal condition affects 1 in 10,000 individuals in a random-mating population. The expected frequency of carriers is approximately:✓ 1 in 50
Q19. The Hardy-Weinberg principle predicts no change in allele frequencies when:✓ No evolutionary process is at work
Q20. Match each Hardy-Weinberg term with what it represents and select the correct option.✓ A-ii, B-iv, C-i, D-iii