GI-Tract Tissue Metabolism

20 questions • 1 test • tap a section to begin

Welcome! 10.2 GI-Tract Tissue Metabolism — 20 questions, CSIR-NET style.

What this test covers

  • Glutamine as the enterocyte's main fuel
  • Absorption: glucose, fat, B12, iron
  • Gut hormones (gastrin, secretin, CCK, incretins)
  • Bile salts and the enterohepatic circulation

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10.2 GI-Tract Tissue Metabolism — Test 1
Q1. The preferred metabolic fuel of intestinal enterocytes is:✓ Glutamine
Q2. Gastrin, which stimulates gastric acid secretion, is released by:✓ G cells of the stomach
Q3. Secretin, released when acid enters the duodenum, stimulates:✓ Pancreatic bicarbonate secretion
Q4. Cholecystokinin (CCK) causes:✓ Gallbladder contraction and pancreatic enzyme release
Q5. Absorption of vitamin B12 requires intrinsic factor secreted by:✓ Gastric parietal cells
Q6. Dietary iron is absorbed mainly in the:✓ Duodenum
Q7. Match each gut hormone with its action and choose the correct option.✓ A-ii, B-i, C-iii
Q8. Bile salts aid fat digestion by:✓ Emulsifying fats to increase the surface area for lipase
Q9. The enterohepatic circulation refers to:✓ Reabsorption of bile salts in the ileum and return to the liver
Q10. Glucose is absorbed across the intestinal brush border mainly via:✓ The sodium-glucose cotransporter (SGLT1)
Q11. The incretin hormones GIP and GLP-1 are released from the gut to:✓ Potentiate glucose-stimulated insulin secretion
Q12. Absorption of fat-soluble vitamins (A, D, E, K) requires:✓ Bile salts (and normal fat absorption)
Q13. Ghrelin, which stimulates appetite, is produced mainly by the:✓ Stomach
Q14. Pernicious anaemia results from autoimmune loss of:✓ Intrinsic factor (parietal-cell destruction)
Q15. The rapid turnover of the intestinal epithelium is supported metabolically by:✓ High glutamine utilization
Q16. Somatostatin in the gut acts to:✓ Inhibit secretion of multiple GI hormones
Q17. The gut is increasingly recognised as an endocrine organ because it:✓ Secretes many hormones (gastrin, secretin, CCK, GLP-1, ghrelin)
Q18. Protein digestion in the stomach begins with:✓ Pepsin activated by gastric acid
Q19. Hepcidin reduces iron absorption from the gut by:✓ Causing degradation of the iron exporter ferroportin
Q20. The overall metabolic role of the GI tract includes:✓ Nutrient absorption plus secretion of hormones that coordinate metabolism