10.3 Liver Metabolism & Failure

Start Here Introduction ▾

Welcome! 10.3 Liver Metabolism & Failure — 20 questions, CSIR-NET style.

Tap the test below — it opens on its own full screen. Use ← All tests at the top to come back.
Each question has a 40-second timer. Answer, then Submit to see your score.
Tap 📋 View Solution under any question for a full explanation.

Open Review at the bottom for a quick revision list of every question with its correct answer.

All 20 Questions Review ▾

Quick revision: every question with its correct answer. For the full explanation, open the test and tap View Solution.

10.3 Liver Metabolism & Failure — Test 1

Q1. The liver maintains blood glucose between meals chiefly by:✓ Glycogenolysis and gluconeogenesis

Q2. The liver can release free glucose into the blood because it has:✓ Glucose-6-phosphatase

Q3. The liver detoxifies ammonia from amino-acid metabolism by the:✓ Urea cycle

Q4. In liver failure, the accumulation of ammonia contributes to:✓ Hepatic encephalopathy

Q5. The liver conjugates bilirubin with glucuronic acid to make it:✓ Water-soluble for excretion

Q6. Ketone bodies are synthesized by the liver but the liver cannot use them because it lacks:✓ Thiophorase (the enzyme to reactivate ketones)

Q7. Match each liver function with its product/marker and choose the correct option.✓ A-ii, B-iii, C-i

Q8. The liver synthesizes most plasma proteins, including:✓ Albumin and clotting factors

Q9. In liver failure, a prolonged prothrombin time reflects:✓ Reduced synthesis of clotting factors

Q10. The Cori cycle involves the liver converting:✓ Lactate (from muscle) back to glucose

Q11. The first hydroxylation of vitamin D (to 25-OH-D) occurs in the:✓ Liver

Q12. In the fed state, the liver:✓ Synthesizes glycogen and fat (lipogenesis)

Q13. During fasting, the liver supplies glucose first by ___ then by ___.✓ glycogenolysis; gluconeogenesis

Q14. The glucose-alanine cycle transfers ___ from muscle to liver for gluconeogenesis.✓ alanine (carrying amino nitrogen)

Q15. Hypoglycaemia in severe liver failure occurs because the liver cannot:✓ Maintain gluconeogenesis/glycogen stores

Q16. Most cholesterol and bile acid synthesis occurs in the:✓ Liver

Q17. The liver's role in drug metabolism involves:✓ Phase I (oxidation) and phase II (conjugation) reactions

Q18. Jaundice with raised conjugated bilirubin, pale stools and dark urine indicates:✓ Post-hepatic (obstructive) cause

Q19. The liver is central to nitrogen disposal because it:✓ Converts amino-acid nitrogen to urea for renal excretion

Q20. Overall, the liver functions as the body's:✓ Central metabolic processing and detoxifying organ