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9.2 Male Reproduction — Test 1
Q1. Testosterone is secreted by the testicular:✓ Leydig cells
Q2. LH (luteinizing hormone) acts on the testis to:✓ Stimulate Leydig cells to produce testosterone
Q3. FSH (follicle-stimulating hormone) acts on the testis to:✓ Stimulate Sertoli cells (supporting spermatogenesis)
Q4. The hormone that induces spermatogenesis/sperm differentiation (with testosterone) is:✓ FSH
Q5. Inhibin, secreted by Sertoli cells, provides negative feedback specifically on:✓ FSH
Q6. Which hormone shows negative feedback in spermatogenesis (on FSH)?✓ Inhibin
Q7. Match each cell/hormone with its role and choose the correct option.✓ A-ii, B-i, C-iii
Q8. Inhibin is commonly produced by which endocrine structure?✓ The gonads
Q9. Sertoli cells nurse developing sperm and also form the:✓ Blood-testis barrier
Q10. Testosterone feedback acts mainly to inhibit:✓ GnRH and LH
Q11. Spermatogenesis requires high LOCAL concentrations of:✓ Testosterone (within the testis)
Q12. Sertoli cells secrete androgen-binding protein (ABP) to:✓ Maintain high local testosterone in the tubule
Q13. Loss of negative feedback (e.g. after castration) causes anterior-pituitary changes called:✓ Castration cells (enlarged gonadotrophs)
Q14. Which describes the dual control of the testis?✓ LH -> Leydig (testosterone); FSH -> Sertoli (spermatogenesis)
Q15. FSH deficiency in a male would most directly impair:✓ Spermatogenesis (germ-cell maturation)
Q16. The principal androgen acting within the prostate is:✓ Dihydrotestosterone (DHT)
Q17. Anabolic-androgenic steroid abuse suppresses spermatogenesis because it:✓ Suppresses LH/FSH (and intratesticular testosterone falls)
Q18. Both Leydig and Sertoli cells are needed because:✓ Leydig provide testosterone that Sertoli cells use to support sperm
Q19. Inhibin levels can serve as a marker of:✓ Sertoli-cell (spermatogenic) function
Q20. The hypothalamic-pituitary-testicular axis is regulated by:✓ Testosterone (on LH) and inhibin (on FSH) negative feedback