4.1 Types of Mutations — Test 1

Start Here Introduction ▾

Welcome! 4.1 Types of Mutations — Test 1 — 20 questions, CSIR-NET style.

Tap the test below — it opens on its own full screen. Use ← All tests at the top to come back.
Each question has a 40-second timer. Answer, then Submit to see your score.
Tap 📋 View Solution under any question for a full explanation.

Open Review at the bottom for a quick revision list of every question with its correct answer.

All 20 Questions Review ▾

Quick revision: every question with its correct answer. For the full explanation, open the test and tap View Solution.

4.1 Types of Mutations — Test 1

Q1. A base substitution that replaces a purine with a pyrimidine (or vice versa) is called a:✓ Transversion

Q2. A point mutation in which one purine is replaced by another purine is classified as a:✓ Transition

Q3. A mutation in which a purine nucleotide is replaced by a pyrimidine is a:✓ Transversion

Q4. A single-nucleotide change that produces a codon specifying a different amino acid is a:✓ Missense mutation

Q5. A base-pair change in which the altered codon still specifies the same amino acid is a:✓ Silent (synonymous) mutation

Q6. A silent mutation results in:✓ No change in the amino acid sequence of the protein

Q7. Which is an example of a synonymous (silent) substitution?✓ TCC → TCA (Ser → Ser)

Q8. Which codon change is most likely to be disruptive to protein synthesis/function?✓ UAU → UAA

Q9. Which point mutation is most likely to severely affect protein function?✓ CAA → TAA

Q10. A frameshift mutation occurs following:✓ Insertion or deletion of a base (not a multiple of three)

Q11. Sickle-cell anaemia is a classic example of which kind of mutation?✓ Point (missense) mutation

Q12. A back mutation restores the original phenotype by changing the:✓ Nucleotide pair (back to the original)

Q13. Which is an example of a point mutation?✓ Substitution of one nucleotide for another

Q14. Transversion is a type of:✓ Point mutation

Q15. A mutant gene encodes a protein that is missing its last three amino acids. The most likely mutation type is:✓ Nonsense

Q16. A mutation that produces an entirely new trait, or causes a trait to appear at an inappropriate time or tissue, is a:✓ Gain-of-function mutation

Q17. A mutation that gives an altered phenotype even in the presence of a wild-type copy of the gene is:✓ A dominant mutation

Q18. Most newly arising mutations are:✓ Harmful and recessive

Q19. Silent (synonymous) substitutions most commonly occur at which codon position?✓ Third position (wobble)

Q20. Match each mutation with its description and select the correct option.✓ A-iii, B-i, C-ii, D-iv