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6.2 Hardy-Weinberg Calculations — Test 1
Q1. In a population at HWE, the dominant-allele frequency is 0.6. The frequency of heterozygous individuals is:✓ 0.48
Q2. In a random sample of 400 individuals at HWE, 36 are homozygous recessive (aa). How many are expected to carry at least one dominant allele A?✓ 364
Q3. A large random-mating population has 4% recessive (affected) individuals. The expected carrier frequency is:✓ 32%
Q4. In a population of 500 diploid individuals, 400 T alleles are counted at a locus. The number of t alleles present is:✓ 600
Q5. A population of 2000 plants has 100 rr (white), 800 Rr (pink) and 1100 RR (red). The frequency of the r allele is:✓ 0.25
Q6. In a sample of 110 individuals (65 BB, 30 Bb, 15 bb), the frequency of the b allele is:✓ 0.27
Q7. In a population of 1000 individuals (600 MM, 300 MN, 100 NN), the frequencies of M and N are:✓ M 0.75, N 0.25
Q8. In a population of 1000 dogs (360 BB, 480 Bb, 160 bb), the frequency of the b allele is:✓ 0.4
Q9. MN blood-type counts are 1787 M, 3039 MN and 1303 N (total 6129). The frequency of the L^N allele is approximately:✓ 0.4605
Q10. At HWE, the genotype frequencies are f(A1A1) = 0.59, f(A1A2) = 0.16, f(A2A2) = 0.25. The allele frequencies are:✓ A1 = 0.67, A2 = 0.33
Q11. At HWE, the frequency of one homozygous genotype is 0.64. The heterozygote frequency is:✓ 0.32
Q12. At HWE, the total frequency of homozygotes is 0.68. The two allele frequencies are:✓ 0.2 and 0.8
Q13. At HWE, a two-allele locus has a heterozygote frequency of 0.32. The frequency of the rarer allele is:✓ 0.2
Q14. In a random-mating population, allele Y has frequency 0.70. The frequency of Y/y heterozygotes is:✓ 0.42
Q15. An autosomal recessive disorder at HWE has an incidence of 1 in 6400. The approximate carrier frequency is:✓ 1 in 40
Q16. An autosomal recessive condition affects 1 in 10,000 newborns. The expected carrier frequency is approximately:✓ 1 in 50
Q17. In a population where 1 in 400 people has a recessive disorder, the expected proportion of carriers is:✓ 38/400
Q18. An X-linked recessive disease has a frequency of 0.16 among females. Its frequency among males is:✓ 0.4
Q19. The frequency of males affected by an X-linked recessive disorder is 0.1. The frequency of affected females is:✓ 0.01
Q20. Match each scenario with its computed value and select the correct option.✓ A-iii, B-i, C-iv, D-ii