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1.4 Primary & Secondary Lymphoid Organs — Test 1
Q1. The thymus is the site of maturation of:✓ T lymphocytes
Q2. In birds, B-cell maturation occurs in the:✓ Bursa of Fabricius
Q3. Hassall's corpuscles are a histological feature of the:✓ Thymic medulla
Q4. Positive and negative selection of developing T cells occurs in the:✓ Thymus (cortex and medulla)
Q5. The periarteriolar lymphoid sheath (PALS) of the spleen is rich in:✓ T cells
Q6. The spleen primarily filters:✓ Blood
Q7. Lymph nodes are responsible for filtering:✓ Lymph
Q8. In a lymph node, B-cell follicles are located in the:✓ Cortex
Q9. The paracortex of a lymph node is enriched in:✓ T cells
Q10. Germinal centres are the sites of:✓ B-cell proliferation, somatic hypermutation and selection
Q11. High endothelial venules (HEVs) function to:✓ Allow lymphocytes to enter lymph nodes from blood
Q12. MALT stands for:✓ Mucosa-associated lymphoid tissue
Q13. Peyer's patches are aggregates of lymphoid tissue located in the:✓ Small intestine (ileum)
Q14. The tonsils are part of which tissue category?✓ MALT (Waldeyer's ring)
Q15. Which is the largest collection of lymphoid tissue in the body?✓ Mucosa-associated lymphoid tissue
Q16. M (microfold) cells overlying Peyer's patches function to:✓ Transport luminal antigen to underlying lymphoid cells
Q17. The lymphatic system ultimately returns lymph to the blood via the:✓ Thoracic duct
Q18. Which pair are BOTH secondary lymphoid organs?✓ Spleen and lymph nodes
Q19. The thymus reaches its maximal size at about:✓ Puberty, then involutes
Q20. The principal site of lymphocyte activation (antigen encounter) is the:✓ Lymph nodes (secondary lymphoid organs)
Q21. Match each lymphoid organ with its function and select the correct option.✓ A-i, B-ii, C-iii, D-iv