Myeloid & Accessory Cells

21 questions β€’ 1 test β€’ tap a section to begin

Welcome! 2.2 Myeloid & Accessory Cells β€” Test 1 — 21 questions, CSIR-NET style.

What this test covers

  • Neutrophils: phagocytosis, respiratory burst, NETs
  • Monocytes/macrophages (M1/M2) & mononuclear phagocyte system
  • Eosinophils, basophils, mast cells
  • Dendritic/accessory cells, opsonisation, co-stimulation

How to use

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Quick revision: every question with its correct answer. For the full explanation, open the test and tap View Solution.

2.2 Myeloid & Accessory Cells β€” Test 1
Q1. The most abundant circulating leukocyte and a key first responder to bacterial infection is the:βœ“ Neutrophil
Q2. Neutrophils kill ingested microbes by all of the following EXCEPT:βœ“ Secreting antibody
Q3. Monocytes that migrate into tissues differentiate into:βœ“ Macrophages (and some dendritic cells)
Q4. Macrophages contribute to adaptive immunity by:βœ“ Presenting antigen on MHC II to CD4 T cells
Q5. Eosinophils are particularly important in defence against:βœ“ Helminth (worm) parasites
Q6. Basophils and mast cells release histamine and are central to:βœ“ Immediate (type I) hypersensitivity and allergy
Q7. The mononuclear phagocyte system consists chiefly of:βœ“ Monocytes and tissue macrophages
Q8. Tissue-resident macrophages with specific names include all of the following EXCEPT:βœ“ Plasma cells
Q9. The respiratory burst in phagocytes is generated by the enzyme:βœ“ NADPH oxidase
Q10. Opsonisation enhances phagocytosis because phagocytes have receptors for:βœ“ Antibody Fc and complement C3b
Q11. Dendritic cells are described as 'accessory cells' because they:βœ“ Capture and present antigen to activate T cells (linking innate and adaptive immunity)
Q12. M1 (classically activated) macrophages, induced by IFN-Ξ³, are specialised for:βœ“ Pro-inflammatory, microbicidal activity
Q13. M2 (alternatively activated) macrophages, induced by IL-4, are specialised for:βœ“ Tissue repair, angiogenesis and resolution of inflammation
Q14. Neutrophil extracellular traps (NETs) are:βœ“ Webs of DNA and antimicrobial proteins that ensnare microbes
Q15. Plasmacytoid dendritic cells are notable for producing large amounts of:βœ“ Type I interferons (IFN-Ξ±/Ξ²)
Q16. Mast cells differ from basophils mainly in that mast cells:βœ“ Are tissue-resident, while basophils circulate in blood
Q17. Neutrophils are recruited from blood into infected tissue by a process involving:βœ“ Rolling, adhesion (selectins/integrins) and transmigration
Q18. Macrophages secrete cytokines such as IL-1, IL-6 and TNF-Ξ± that drive:βœ“ Inflammation and the acute-phase response
Q19. Accessory cells provide a 'second signal' (co-stimulation) to T cells via molecules such as:βœ“ B7 (CD80/CD86) engaging CD28
Q20. Which leukocyte is characterised by azurophilic (primary) granules?βœ“ Neutrophils
Q21. Match each myeloid/accessory cell with its key feature and select the correct option.βœ“ A-ii, B-iii, C-iv, D-i