The complement system acts as a crucial mediator of innate immunity and inflammation. Its inflammatory role is primarily mediated through the generation of bioactive peptide fragments known as anaphylatoxins, especially C3a and C5a. These molecules link pathogen recognition to vascular,…
The complement system is a group of more than 30 heat-labile plasma proteins that play a crucial role in host defense. These proteins circulate in an inactive form and become activated in a sequential enzymatic cascade. The complement system enhances…
The Classical Pathway of Complement Activation is one of the most important mechanisms of the immune system. It acts as a bridge between adaptive immunity (antibodies) and innate immunity (complement proteins).This pathway is called classical because it was the first…