Molecular Biology

Topic-wise MCQ Quiz

All Modules

1

Genome Organization & Chromatin

155 questions · 5 topics · all live

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1.1 Genome Size & Complexity · 20 Q

C-value paradox · Cot curves · Repetitive DNA

1.2 Gene Architecture & Pseudogenes · 20 Q

Pseudogenes · Gene families · Organelle genome

1.3 Chromatin Structure & Remodeling · 36 Q

Nucleosome · Histones · Remodeling

1.4 Chromosome Anatomy · 20 Q

Centromere · Telomere · Organization

1.5 DNA Structure & Properties · 59 Q

Double helix · Tm · Supercoiling · Chargaff

2

DNA Replication, Repair & Recombination

229 questions · 4 topics · all live

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2.1 Prokaryotic DNA Replication · 93 Q

oriC · DNA polymerases · Okazaki · Proofreading

2.2 Eukaryotic DNA Replication · 20 Q

Replicons · ORC · PCNA · Pol δ/ε · Telomerase

2.3 DNA Damage & Repair · 86 Q

NER · BER · Mismatch · SOS · Direct repair

2.4 Recombination · 30 Q

Homologous · Holliday · RecA · DSBR · Site-specific

3

Mobile DNA Elements

60 questions · 3 topics · all live

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3.1 Bacterial Transposable Elements · 20 Q

IS elements · Composite transposons · Replicative/non-replicative

3.2 Transposition Mechanisms & Control · 20 Q

Mu · Tn3 · Tn10 control · DDE transposase

3.3 Eukaryotic Mobile Elements · 20 Q

LINEs · SINEs · Retrotransposons · Retroviruses

4

Transcription & RNA Processing

235 questions · 4 topics · all live

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4.1 Prokaryotic Transcription · 19 Q

RNA polymerase · Sigma factors · Promoters · Rho termination

4.2 Eukaryotic Transcription · 30 Q

RNA Pol I/II/III · TFIIs · TATA box · CTD

4.3 Regulation of Transcription · 96 Q

lac/trp operons · Attenuation · Enhancers · TF domains

4.4 RNA Processing · 90 Q

Splicing · Spliceosome · RNA editing · Capping & poly-A

5

Translation & Gene-Expression Regulation

147 questions · 4 topics · all live

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5.1 Prokaryotic Translation · 73 Q

Genetic code · Ribosome · tRNA · Initiation/elongation/termination

5.2 Eukaryotic Translation · 19 Q

eIFs · Kozak · eEF2 · Cap-dependent initiation

5.3 Chromatin & Epigenetic Regulation · 20 Q

Heterochromatin · X-inactivation · Imprinting · Histone marks

5.4 Translational Regulation · 35 Q

mRNA stability · IRES · eIF2 · miRNA · RNAi

6

Recombinant DNA, Genomics & Proteomics

223 questions · 6 topics · all live

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6.1 Gene Cloning Strategy · 19 Q

Genomic/cDNA libraries · DNA isolation · characterization

6.2 Vectors & Gene Transfer · 68 Q

Plasmids/cosmids/YAC/BAC · Restriction enzymes · PCR · Transfer

6.3 Screening, Sequencing & Expression · 45 Q

Hybridization · Probes · CRISPR · Expression hosts

6.4 Genomics & Sequencing · 45 Q

Sanger/Maxam-Gilbert/NGS · Mapping · Restriction-site frequency

6.5 Global Expression & Proteomics · 31 Q

RNA-Seq · Microarray · 2D PAGE · Mass spec · PPI

★ CSIR-NET Challenge · 15 Q

Lengthy scenario & multi-statement CSIR-NET questions